Ingredient · INCI listed
Tranexamic Acid
Tranexamic acid reduces melanin transfer from melanocytes to keratinocytes, addressing hyperpigmentation at a different step than most brightening agents. Originally a blood-clotting drug, it's become a standout ingredient for melasma and dark spots.
Evidence — Well-established
Data summary
Products containing
43
Most common in
21 products
serums
Typical pairing
Niacinamide (Vitamin B3)
Evidence level
Well-established for melasma (oral form). Growing evidence for topical use at 2-5%. Particularly effective for hormonal and inflammatory hyperpigmentation where other brightening agents fall short.
Verified reviewer
Where it shows up
