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ZO Skin Health

ZO Skin Health was founded in 2007 by Dr. Zein Obagi, a board-certified dermatologist with decades of clinical practice. The brand is sold primarily through dermatology offices and medspas, and many of its formulas were developed alongside in-office protocols.

DermFND
Verified house
15 of 16 products signed off
Products reviewed
16
Average score
71.1/100
Median price
$112
Top category
serum
Last reviewed
May 2026
Alex Brufsky
Alex Brufsky Founder & Editor
Analysis by DermFND · Last verified May 2026 · Methodology
Verified reviewer
16 products viewing all categories
The DermFND take

ZO Skin Health, by the numbers.

ZO Skin Health has 16 products in the DermFND database, concentrated in serums, treatments, and retinoids. Observed ingredient patterns across the database show vitamin c, retinol, peptides, vitamin e, urea, salicylic acid, niacinamide, and squalane as the most common components. The price range for these products is $50 to $265, with an average price of $118. The brand maintains an average DermFND score of 71.1/100. Sample products include Daily Power Defense, Brightalive Skin Brightener, 10% Vitamin C Self-Activating, Body Emulsion, and Smart Tone Broad Spectrum SPF 50.

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