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iS Clinical

iS Clinical was co-founded in 2002 by biochemist Bryan Johns and Alec Call. The brand is rooted in pharmaceutical-grade formulation and is distributed through dermatologists, plastic surgeons, and medical spas in over 125 countries.

DermFND
Verified house
14 of 14 products signed off
Products reviewed
14
Average score
75.2/100
Median price
$125
Top category
serum
Last reviewed
May 2026
Alex Brufsky
Alex Brufsky Founder & Editor
Analysis by DermFND · Last verified May 2026 · Methodology
Verified reviewer
14 products viewing all categories
The DermFND take

iS Clinical, by the numbers.

iS Clinical has 14 products in the DermFND database, concentrated in serums, cleansers, sunscreens, eye creams, and moisturizers. Observed ingredient patterns across these formulations frequently include hyaluronic acid, centella asiatica, vitamin e, peptides, glycolic acid, vitamin c, salicylic acid, and green tea. The brand's price range spans from $49 to $256, with an average product price of $122. The typical product profile maintains an average DermFND score of 75.2/100. Sample items within the database include Cleansing Complex, Eclipse SPF 50+, Extreme Protect SPF 40, Youth Eye Complex, and C Eye Serum Advance+.

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