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Clinique Moisture Surge Intense 72H Lipid-Replenishing Hydrator rich cream in pink glass jar

Moisture Surge Intense 72H Lipid-Replenishing Hydrator

Dry Skin Winter Savior

luxury Fragrance Free Paraben Free Pregnancy Safe Not Cruelty Free
72/100
DermFND score
Ingredient quality
7.6
Value for money
7.4
Suitability breadth
5.4
Irritation risk
Med
$47.00
1.7 oz / 50 mL · other sizes available
4.4
5,000 customer ratings (Amazon)
Data confidence
High confidence
5,000+ aggregated reviews · INCI confirmed
Launched
2019
Best season
fall-
PAO
12 mo.
after opening
Certifications
Allergy Tested
+2 more
Alex Brufsky
Alex Brufsky Founder & Editor
Analysis by DermFND · Last verified May 2026 · Methodology
Verified reviewer
01 · Quick read

Pros & cons.

What we love
  • +Lipid trio of squalane, cholesterol, and linoleic acid provides genuine barrier repair
  • +Petrolatum occlusion locks in hydration with unmatched effectiveness
  • +Centella asiatica soothes irritated, reactive, barrier-compromised skin
  • +Rich texture absorbs well without feeling heavy, greasy, or suffocating
  • +Fragrance-free and allergy-tested with excellent tolerability for sensitive dry skin
  • +Clinically tested in extreme winter conditions for validated hydration claims
  • +Multiple size options including a 4.2 oz value jar for committed users
What to know
  • Too rich for oily and most combination skin types — use the 100H instead
  • Jar packaging is less hygienic than tube format for barrier-compromised skin
  • Contains isopropyl isostearate which has some comedogenic potential
  • Whey protein and wheat bran extract may concern those with specific allergies
  • Prestige pricing for a formula built on well-established, non-exotic ingredients
02 · Editorial analysis

The full review.

Clinique sent this moisturizer to Siberia. Part marketing, part science, the goal was to see if a prestige moisturizer keeps skin hydrated when the air pulls moisture from the face. Women in a real Siberian winter tested The Moisture Surge Intense 72H Lipid-Replenishing Hydrator, and those results back its hydration claims. Testing a moisturizer in one of the world’s coldest, driest environments shows confidence in the formula.

That confidence is earned. While The Moisture Surge 100H is a lightweight gel-cream using humectants to attract water, The Intense 72H uses a different approach. It contains humectants like hyaluronic acid, glycerin, hydroxyethyl urea, and trehalose, but adds a lipid-replenishing system to fix why dry skin stays dry.

The combination of squalane, cholesterol, and linoleic acid is intentional. These three lipids exist in the skin’s intercellular matrix—the mortar between cells that stops water from escaping. When cold weather, harsh cleansers, aging, or genetics deplete this lipid matrix, humectants cannot hold moisture. Water enters, then escapes. The Intense 72H fixes this by replenishing structural lipids first, creating a repaired foundation for the humectants.

Petrolatum seals the barrier. As dermatology’s most proven occlusive, petrolatum creates a physical layer that prevents transepidermal water loss efficiently. Its presence shows Clinique prioritizes barrier repair; petrolatum isn’t glamorous, but it works.

Centella asiatica (cica) soothes dry, compromised skin. Damaged barriers cause skin to become red, tight, and stinging. Cica’s anti-inflammatory properties calm this reactivity while the lipids rebuild the barrier. It treats the irritation and the cause simultaneously.

The texture balances thickness and wearability. A small amount from the jar is a dense, velvety cream, thicker than the 100H gel. As you massage it in, the cream melts without tugging, absorbs in minutes, and leaves a dewy finish that feels protective but not suffocating. It is not a heavy, greasy cream that sits on the skin. It is an emulsion that deposits lipids and humectants, then settles into an invisible, comfortable layer.

Dry skin users see results immediately. The tight, uncomfortable feeling disappears seconds after application. Flaking patches calm within the first few days. After two to three weeks of consistent use, baseline hydration improves—your face feels less thirsty even before application. This shows the lipid repair is working and your barrier holds moisture better.

The Intense 72H works as a rescue cream for harsh winters, dry climates, or retinol-induced dryness. At night, applying it over retinol buffers irritation and maintains hydration. In the morning, it creates a smooth, hydrated canvas that holds makeup all day.

The limitations are clear. This cream is not for oily skin. The lipids, petrolatum, and isopropyl isostearate feel heavy and may cause congestion on skin with adequate sebum. Combination skin can use it on dry areas while avoiding the T-zone, but the lighter 100H is better for most combination types.

The jar packaging is the same glass jar used for the Moisture Surge line, which has hygiene concerns. Opening the lid to use fingers or a spatula introduces air and bacteria. A tube or pump would suit a formula for barrier-compromised, sensitive skin better.

At $47 for the 1.7-ounce jar, the price matches the 100H—reasonable for prestige, but not a bargain. The 4.2-ounce jar has better per-ounce value for year-round dry skin users. The 0.5-ounce travel size works for testing or carry-ons.

The Intense 72H fills a different role than its lightweight sibling. If the 100H is for everyone, the Intense 72H is for those who need it most. It lacks trendy actives or minimalism, but it reliably repairs a damaged barrier, restores lipids, and keeps dry skin comfortable in extreme conditions. Siberia approved.

Formula

Texture

The texture balances thickness and wearability. A small amount from the jar is a dense, velvety cream, thicker than the 100H gel. As you massage it in, the cream melts without tugging, absorbs in minutes, and leaves a dewy finish that feels protective but not suffocating. It is not a heavy, greasy cream that sits on the skin. It is an emulsion that deposits lipids and humectants, then settles into an invisible, comfortable layer.

Best for

The Intense 72H works as a rescue cream for harsh winters, dry climates, or retinol-induced dryness. At night, applying it over retinol buffers irritation and maintains hydration. In the morning, it creates a smooth, hydrated canvas that holds makeup all day.

Not ideal for

The limitations are clear. This cream is not for oily skin. The lipids, petrolatum, and isopropyl isostearate feel heavy and may cause congestion on skin with adequate sebum. Combination skin can use it on dry areas while avoiding the T-zone, but the lighter 100H is better for most combination types.

Packaging

The jar packaging is the same glass jar used for the Moisture Surge line, which has hygiene concerns. Opening the lid to use fingers or a spatula introduces air and bacteria. A tube or pump would suit a formula for barrier-compromised, sensitive skin better.

03 · INCI · disclosed by brand

Ingredient analysis.

Ingredient Role Evidence Flag
Three barrier-repairing lipids that work together to replenish the intercellular lipid matrix of dry, compromised skin. Squalane mirrors skin's own sebum, cholesterol strengthens the mortar between skin cells, and linoleic acid — an essential fatty acid often deficient in dry skin — restores the lipid balance. This trio is what distinguishes the Intense 72H from the lighter 100H formula.
Well Established
OK
Provides targeted soothing for the irritation and inflammation that dry, barrier-compromised skin frequently experiences. In this lipid-rich formula, cica calms reactive skin while the lipid trio rebuilds the structural barrier — addressing both the symptom (irritation) and the cause (lipid depletion) simultaneously.
Well Established
OK
Draws and binds water in the skin's upper layers, providing the humectant hydration component that complements the lipid-based barrier repair. In this richer formula, the hyaluronic acid ensures skin gets both water-based hydration and oil-based moisture — the dual approach that severely dry skin requires.
Well Established
OK
The gold standard occlusive ingredient that creates a physical barrier to prevent transepidermal water loss. Its inclusion signals that this formula is serious about moisture retention — petrolatum is the single most effective ingredient at locking in hydration, and it anchors the barrier-repair strategy of this cream.
Well Established
OK
A non-irritating humectant that enhances the skin's natural moisturizing factor. Works alongside the glycerin, trehalose, and sorbitol to create a multi-humectant reservoir that draws moisture from the environment and holds it in the skin — the hydration engine that powers the 72-hour claim.
Well Established
OK
Full INCI list

Water, Glycerin, Dimethicone, Isopropyl Isostearate, Dipropylene Glycol, Squalane, PEG/PPG-18/18 Dimethicone, Silica, Tocopheryl Acetate, Sodium Hyaluronate, Olea Europaea Fruit Extract, Centella Asiatica Extract, Aloe Barbadensis Leaf Water, Palmitoyl Hexapeptide-12, Triticum Vulgare Bran Extract, Caffeine, Methyl Trimethicone, Sorbitol, Sodium Polyaspartate, Petrolatum, Trehalose, Whey Protein, Linoleic Acid, Pyridoxine Dipalmitate, Butylene Glycol, Cholesterol, Sucrose, Polysilicone-11, Glyceryl Polymethacrylate, PEG-150, PEG-8, Hydroxyethyl Urea, Hydroxyacetophenone, BHT, Disodium EDTA, Sodium Hexametaphosphate, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol

Product flags
✓ Fragrance Free ✓ Alcohol Free ✗ Oil Free ✗ Silicone Free ✓ Paraben Free ✓ Sulfate Free ✗ Cruelty Free ✗ Vegan ✗ Fungal Acne Safe
04 · Compatibility

Skin match.

Pairs well with
hyaluronic acid serumsniacinamide serumsretinol treatments (as buffer)ceramide products
Skin types
Best for
dry
Works for
normalcombinationsensitive
Not ideal for
oily
05 · Evidence

The science.

The Science

This formula uses a lipid-replenishing approach based on decades of skin barrier research. The skin's intercellular lipid matrix contains ceramides, cholesterol, and free fatty acids in a roughly 3:1:1 ratio. When environmental damage, harsh cleansing, or dry skin depletes this matrix, transepidermal water loss (TEWL) increases. Research by Elias and Feingold throughout the 1990s and 2000s shows that topical replenishment of these physiological lipids restores barrier function and reduces TEWL.

Squalane acts as a sebum-mimicking emollient that integrates into the skin's natural lipid structure. Research in the Journal of Investigative Dermatology shows that cholesterol, a structural component of the intercellular matrix, accelerates barrier recovery when applied topically. Linoleic acid, an essential omega-6 fatty acid, is often low in dry and acne-prone skin; topical use improves barrier integrity and reduces inflammation.

Petrolatum is the most effective occlusive agent in dermatology. A 1992 study by Ghadially et al. in the Journal of Clinical Investigation shows that petrolatum prevents water loss through occlusion and penetrates the stratum corneum to support lipid synthesis and barrier repair. This dual mechanism—occlusion and active barrier support—makes petrolatum uniquely effective.

Clinical studies validate the wound-healing and anti-inflammatory properties of Centella asiatica. A review in the International Journal of Cosmetic Science notes that cica's active compounds—asiaticoside, madecassoside, asiatic acid, and madecassic acid—stimulate collagen synthesis, reduce inflammation, and accelerate barrier repair. Including it in a barrier-repair moisturizer is pharmacologically sound.

References

  1. Effects of petrolatum on stratum corneum structure and function — Journal of Clinical Investigation (1992)

Dermatologist Perspective

Dermatologists often recommend lipid-replenishing moisturizers for patients with chronically dry or barrier-compromised skin; the Intense 72H formulation follows evidence-based barrier repair principles. Board-certified dermatologists note that combining physiological lipids (squalane, cholesterol, linoleic acid) with petrolatum occlusion effectively restores transepidermal water loss. The fragrance-free, allergy-tested formulation is important for patients with eczema or dermatitis, as fragrance and common sensitizers exacerbate flares. Clinicians typically recommend this as a twice-daily moisturizer for dry to very dry skin, or as an overnight barrier-repair treatment for patients with retinoid-induced dryness.

Guidance

06 · Where it fits

Where it fits in your routine.

AM routine
01 Gentle cream cleanser
02 Hydrating serum
03 Clinique Moisture Surge Intense 72H Lipid-Replenishing Hydrator This product
04 Sunscreen SPF 30+
PM routine
01 Oil cleanser
02 Gentle cream cleanser
03 Treatment serum (retinol/niacinamide)
04 Clinique Moisture Surge Intense 72H Lipid-Replenishing Hydrator This product
How to use

Apply a nickel-sized amount to clean, damp skin after serums. Massage it upward across the face and neck. Use morning and evening. In the morning, follow with sunscreen SPF 30+. At night, use this as your final step. For extra-dry skin or harsh winter conditions, apply a thicker layer as a sleeping mask. Use on dry body patches (elbows, hands) for targeted barrier repair.

Value assessment

At $47 for 1.7 ounces — the same price as the lighter Moisture Surge 100H — the Intense 72H has a more complex formula with cica and barrier-repairing lipids. The 4.2-ounce jar (approximately $72) offers better per-ounce value and is the best buy for users who know this formula works for them. The ingredient list uses established, inexpensive actives; the premium price reflects Clinique's formulation expertise, clinical testing, and brand legacy instead of rare or costly ingredients. For dry skin types using this daily, the cost is roughly $16-24 per month depending on size — reasonable for a prestige moisturizer that repairs barrier function.

Who should buy

Dry to very dry skin types need more than lightweight hydration—especially those with winter dryness, barrier damage, or retinol-induced dryness. It also works for sensitive skin that reacts to fragranced products and anyone seeking a reliable barrier-repair moisturizer from a legacy dermatologist-developed brand.

Who should skip

Oily skin types will find this formula too heavy, and acne-prone skin reacts to the lipid-rich formulation. Normal-to-combination skin types already have enough from the lighter Moisture Surge 100H. Those with wheat or dairy allergies must review the INCI list carefully.

07 · The fine print

Product details.

Texture

A thick, velvety cream with a slightly whipped texture. It is denser than the 100H gel-cream but melts into skin without dragging. It leaves a comfortable, dewy finish without greasiness.

Scent

Fragrance-free with no detectable scent.

Packaging

Pink-tinted glass jar with a screw-top lid matches the Moisture Surge family aesthetic. Sizes range from the 0.5 oz travel size to the 4.2 oz value jar.

First use

Very dry skin feels immediate relief on first application. Tightness and discomfort subside within seconds as the cream melts in. The texture is thicker than the 100H version but still absorbs well. It leaves a dewy, comfortable finish that lasts for hours. It does not sting or tingle, even on irritated, barrier-compromised skin.

How long it lasts

2-3 months with twice-daily use of the 1.7 oz size

Period after opening

12 months

Best season

fall winter

Finish
dewyvelvetynon-greasy
Certifications
Allergy TestedDermatologist TestedFragrance Free
08 · Behind the formula

The backstory.

The Intense variant of Moisture Surge was developed for people whose dry skin couldn't be satisfied by gel-cream textures alone. Clinique tested this formula in some of the harshest winter conditions on earth — Siberia — to prove that it could maintain skin hydration even in extreme cold and low humidity. The results validated the lipid-replenishing approach, showing measurable hydration persistence in conditions that destroy most moisturizers' claims.

About Clinique

Legacy Brand (20+ years)

Clinique launched in 1968 as the first prestige skincare brand created by dermatologists. Clinique tested The Moisture Surge Intense 72H in Siberian winter conditions to prove its extreme-environment hydration claims, showing the brand's commitment to real-world clinical testing.

Brand founded: 1968 · Product launched: 2019
09 · Setting the record straight

Common myths.

Myth

Rich moisturizers always clog pores and cause breakouts.

Reality

This formula contains isopropyl isostearate, which has comedogenic potential, but the formulation absorbs into the skin instead of sitting on top. Many people with dry-combination skin use this without breakouts. Acne-prone and oily skin types should use caution and may prefer the lighter 100H version.

Myth

The 72-hour claim means you moisturize every three days.

Reality

The 72-hour claim describes measurable hydration improvement from one application, not a suggested frequency. Apply morning and evening for optimal barrier repair and hydration. Sustained hydration keeps skin comfortable even if you skip an application.

10 · Common questions

FAQ.

What is the difference between Clinique Moisture Surge 100H and Intense 72H?

The 100H is a lightweight gel-cream that uses humectants to hydrate all skin types, mainly oily and combination. The Intense 72H is a thicker cream with petrolatum and added lipids (squalane, cholesterol, linoleic acid) for dry to very dry skin needing barrier repair. Use the 100H for lightweight hydration and the Intense 72H for deep moisture and barrier restoration.

Is Clinique Moisture Surge Intense 72H good for eczema-prone skin?

Squalane, cholesterol, and centella asiatica make this lipid-replenishing formula support eczema-prone skin. The fragrance-free, allergy-tested formulation reduces sensitization risk. Because it contains whey protein and wheat bran extract, users with specific allergies to these ingredients must check the full INCI list.

Can you use Clinique Moisture Surge Intense 72H with retinol?

Yes — this works well with retinol treatments. The lipid-rich formula buffers retinol's drying and irritating effects, while the barrier-repairing ingredients restore what retinol depletes. Apply retinol first, wait a few minutes, then layer the Intense 72H on top as a protective, hydrating seal.

Is Clinique Moisture Surge Intense 72H oil-free?

No — unlike the lighter 100H version, the Intense 72H contains oil. It uses squalane and isopropyl isostearate as emollient lipids, plus petrolatum as an occlusive. These ingredients replenish lipids and repair the barrier in dry skin.

Can oily skin use Clinique Moisture Surge Intense 72H?

This formula targets dry to very dry skin and feels too heavy for oily skin. The lipids and petrolatum cause shine and clog pores on oily skin. Oily skin types should use the Moisture Surge 100H, which is oil-free and lightweight.

11 · Real-world signal

What the community says.

Common praise

"Provides intense, long-lasting hydration for very dry skin"

"Rich texture without feeling heavy or greasy"

"Eliminates flaking and tight-skin feeling"

"Fragrance-free and non-irritating"

"Works well as a winter moisturizer"

Common complaints

"Too rich for oily or acne-prone skin"

"Prestige pricing for a moisturizer"

"Jar packaging is less hygienic than tubes"

"May feel too heavy in warm, humid weather"

Notable endorsements
Clinically tested in Siberian winter conditionsDermatologist-developedAllergy tested
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