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DefenAge

DefenAge launched in 2016 around a patented peptide platform called Age-Repair Defensins, developed by a team including dermatologist Dr. Adam Geyer and researchers at the University of California. The brand's pivotal 12-week split-face clinical trial was published in the Journal of Drugs in Dermatology in 2018.

DermFND
Verified house
4 of 4 products signed off
Products reviewed
4
Average score
75.5/100
Median price
$206
Top category
moisturizer
Last reviewed
May 2026
Alex Brufsky
Alex Brufsky Founder & Editor
Analysis by DermFND · Last verified May 2026 · Methodology
Verified reviewer
4 products viewing all categories
The DermFND take

DefenAge, by the numbers.

DefenAge has 4 products in the DermFND database, distributed across moisturizer, serum, treatment, and mask categories. Observed ingredient patterns across these products include defensins, peptides, niacinamide, enzymes, squalane, shea butter, coenzyme q10, and ceramides. The price range for these items is $88 to $365, with an average price of $188. The brand maintains an average DermFND score of 75.5/100. Sample products within the database include the 24/7 Barrier Balance Cream, 8-in-1 BioSerum, Clinical Power Trio, and 2-Minute Reveal Masque. This data represents the current product profile for DefenAge within our analytical records.

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