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111Skin

111Skin was founded in 2012 by Dr. Yannis Alexandrides, a Harley Street plastic surgeon, who originally developed the NAC Y2 formula to help his post-procedure patients heal faster. The brand has clinical credibility from its surgical origins, though independent peer-reviewed validation of the proprietary NAC Y2 complex specifically remains limited.

DermFND
Verified house
4 of 4 products signed off
Products reviewed
4
Average score
65.8/100
Median price
$135
Top category
serum
Last reviewed
May 2026
Alex Brufsky
Alex Brufsky Founder & Editor
Analysis by DermFND · Last verified May 2026 · Methodology
Verified reviewer
4 products viewing all categories
The DermFND take

111Skin, by the numbers.

111Skin has 4 products in the DermFND database, concentrated in serums and masks. Observed ingredient patterns across these products include niacinamide, n acetyl cysteine, hyaluronic acid, vitamin c, retinol, peptides, glutathione, and gold. The price range for these items is $120 to $188, with an average price of $144. The brand maintains an average DermFND score of 65.8/100. Sample products within the database include the Repair Serum NAC Y2, Celestial Black Diamond Eye Mask, Rose Gold Brightening Facial Treatment Mask, and Hyaluronic Acid Aqua Booster. This data reflects a specific concentration of active ingredients within a limited product selection.

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